Polygalacic acid 7781 InChi: InChI=1S/C20H21N7O2S/c1-12-4-5-14(10-18(12)30(21

InChi: InChI=1S/C20H21N7O2S/c1-12-4-5-14(10-18(12)30(21

This conclusion was supported by in vivo experiments that shows that: 1) ablation of corticosteroids by use of Mifepristone or adrenalectomy suppress the effect of SR-31747

but only activatedRARβ and RARγ with about 10% efficacy at the highest dose (1000 nM) tested

1 μM and higher all give a maximum transduction

Polygalacic acid 7781 InChi: InChI=1S/C20H21N7O2S/c1-12-4-5-14(10-18(12)30(21Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and